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Angular cheilitis (or perlèche) is an inflammatory lesion affecting one or both of the labial commissures. The clinical presentation varies from simple erythema to deep cracks with inflammation and crusty or hyperkeratotic scabs on shallow ulcers. The lesions are painful, bleed easily when touched and make it difficult to open the mouth. In the severe forms, the lesions may spread to the vermillion or adjacent skin. Patients must always be examined for complications within the oral cavity (erythema, leukoplakia, gingivitis or glossitis).
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